MBF1 Family
Description
Tsuda et al. 2004: Multiprotein bridging factor 1 (MBF1) is known to be a transcriptional co-activator that mediates transcriptional activation by bridging between an activator and a TATA-box binding protein (TBP). We demonstrated that expression of every three MBF1 from Arabidopsis partially rescues the yeast mbf1 mutant phenotype, indicating that all of them function as co-activators for GCN4-dependent transcriptional activation. We also report that each of their subtypes shows distinct tissue-specific expression patterns and responses to phytohormones. These observations suggest that even though they share a similar biochemical function, each MBF1 has distinct roles in various tissues and conditions.
Members of this familySHOULD possess MBF1 domain
This family is also present in:
- Galdieria sulphuraria
- Micromonas sp. RCC299
- Chlamydomonas reinhardtii
- Chlorella sp. NC64A
- Coccomyxa sp. C-169
- Physcomitrella patens
- Selaginella moellendorffii
- Oryza sativa subsp. indica
- Oryza sativa subsp. japonica
- Sorghum bicolor
- Zea mays
- Arabidopsis lyrata
- Arabidopsis thaliana
- Carica papaya
- Populus trichocarpa
- Vitis vinifera
General references
Tsuda, K; Tsuji, T; Hirose, S; Yamazaki, K. 2004. Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators. Plant Cell Physiol. 45(2):225-31 PUBMEDID:14988493Design qRT-PCR primers using Quantprime