MBF1 Family

Description

Tsuda et al. 2004: Multiprotein bridging factor 1 (MBF1) is known to be a transcriptional co-activator that mediates transcriptional activation by bridging between an activator and a TATA-box binding protein (TBP). We demonstrated that expression of every three MBF1 from Arabidopsis partially rescues the yeast mbf1 mutant phenotype, indicating that all of them function as co-activators for GCN4-dependent transcriptional activation. We also report that each of their subtypes shows distinct tissue-specific expression patterns and responses to phytohormones. These observations suggest that even though they share a similar biochemical function, each MBF1 has distinct roles in various tissues and conditions.

Domain alignments

This family is also present in:

• Galdieria sulphuraria
• Micromonas sp. RCC299
• Chlamydomonas reinhardtii
• Chlorella sp. NC64A
• Coccomyxa sp. C-169
• Physcomitrella patens
• Selaginella moellendorffii
• Oryza sativa subsp. indica
• Oryza sativa subsp. japonica
• Sorghum bicolor
• Zea mays
• Arabidopsis lyrata
• Arabidopsis thaliana
• Carica papaya
• Populus trichocarpa
• Vitis vinifera

References